2026
100. T. Kefela, D. Li, L.C. Van De Werfhorst, R.M Reynolds, R. Behrens, Y. Floyd, J.L. Brown, J. Smith, M.A. O’Malley, P.A. Holden
Bacterial community colonization with minimal alteration of plastics in suboxic sediments from a marine methane seep
Applied and Environmental Microbiology2025
99. R.Ragunathan, H.M. Purdy, S. Seppala, H. Gwak, S. Calhoun, B.S. Twining, I.V. Grigoriev, B.F. Chmelka, M.A. Brzezinksi, M.A. O'Malley.
Increased aluminum exposure induces widespread changes in silicon, carbon, and nitrogen metabolism in Entomoneis vertebralis
BMC Genomics97. T.S. Lankiewicz, B.Amer, E.E.K. Baidoo, P.A. Leggieri, M.A. O’Malley.
The anaerobic fungus Neocallimastix californiae shifts metabolism and produces melanin in response to lignin-derived aromatic compounds
Biotechnology for Biofuels and Bioproducts | 18, Article number: 96 (2025)98. L.V. Butkovich, C.L. Swift, C.S. Clendinen, HM. Olson, S.O. Purvine, O.B. Vining, M.A. O’Malley.
Untargeted GC-MS Metabolic Profiling of Anaerobic Gut Fungi Reveals Putative Terpenoids and Strain-Specific Metabolites
Metabolites96. C.B. Ahern, I. Chen, M. Huntemann, N. Ivanova, N. Kyrpides, S. Mukherjee, K. Palaniappan, C. Pennacchio, T.B.K. Reddy, S. Ritter, A. Spunde, D. Stamatis, P. Wang, T. Woyke, Y. Zhang, M.A. O'Malley.
High-quality draft genome sequence of Thermobifida halotolerans DSM 44931
Microbiology Resource Announcement95. S. Jin, I.R. Farrand, Y. Chen, J.W. Gin, B. Zhang, E. Kirschke, C.J. Petzold, P.D. Adams, M.A. O'Malley.
A large-scale screening campaign of putative carbohydrate-active enzymes reveals a novel xylanase from anaerobic gut fungi
mBio94. E.M. Blair, N.J. Margalith, M.A. O’Malley.
Microbial Enrichments Contribute to Characterization of Desert Tortoise Gut Microbiota
Microbial Ecology93. E.M. Blair, T.A. Navaratna, C.B. Ahern, R. Ragunathan, J.L. Brown, S.J. Mondo, A. Lipzen, R.A. Hanafy, K. LaButti, J. Talag, K. Barry, M. Chovatia, M. Wang, J. Gonzalez, X. Peng, I.V. Grigoriev, M.A. O'Malley.
Genomic and Transcriptomic Characterization of Carbohydrate-Active Enzymes in the Anaerobic Fungus Neocallimastix cameroonii var. constans
G3: Genes, Genomes, Genetics92. T.S. Lankiewicz, N.H. Elisabeth, D.L. Valentine, M.A. O'Malley.
An Argument for Using Anaerobes as Microbial Cell Factories to Advance Synthetic Biology and Biomanufacturing
AIChE Journal (Cover Article)91. L.V. Butkovich, P.A. Leggieri, S.P. Lillington, T.A. Navaratna, C.L. Swift, N.G. Malinov, T.R. Zalunardo, O.B. Vining, A. Lipzen, M. Wang, J. Yan, V. Ng, I.V. Grigoriev, M.A. O'Malley.
Separation of Life Stages within Anaerobic Fungi (Neocallimastigomycota) Highlights Differences in Global Transcription and Metabolism
Fungal Genetics and Biology90. S. Agarwala, M.A. O’Malley, T. Eng.
Editorial Reflections on BioEnergy: Perspectives from 2024
Current Opinion in Biotechnology89. L.V. Butkovich, O.B. Vining, M.A. O’Malley.
New Approaches to Secondary Metabolite Discovery from Anaerobic Gut Microbes
Applied Microbiology and Biotechnology2024
88. V. Mubayi, C.B. Ahern, M. Calusinska, M.A. O’Malley.
Toward a Circular Bioeconomy: Designing Microbes and Polymers for Biodegradation.
ACS Synthetic Biology87. E.M. Blair, J.L. Brown, D. Li, P.A. Holden, M.A. O'Malley.
Metagenomics Analysis Yields Assembled Genomes from Prokaryotic Anaerobes with Polymer‐Degrading Potential
Biotechnology Progress86. T.A. Navaratna, N. Alansari, A.R. Eisenberg, M.A. O’Malley.
Anaerobic Fungi Contain Abundant, Diverse, and Transcriptionally Active Long Terminal Repeat Retrotransposons
Fungal Genetics and Biology85. H. Doré, A.R. Eisenberg, E.N. Junkins, G.E. Leventhal, A. Ganesh, O.X. Cordero, B.G. Paul, D.L. Valentine, M.A. O'Malley, E.G. Wilbanks.
Targeted Hypermutation of Putative Antigen Sensors in Multicellular Bacteria
Proceedings of the National Academy of Sciences84. N. Liu, V. Kivenson, X. Peng, Z. Cui, T.S. Lankiewicz, K.M. Gosselin, C.J. English, E.M. Blair, M.A. O'Malley, D.L. Valentine.
Pontiella agarivorans sp. nov., a Novel Marine Anaerobic Bacterium Capable of Degrading Macroalgal Polysaccharides and Fixing Nitrogen
Applied and Environmental Microbiology83. P.A. Leggieri, E.M. Blair, T.S. Lankiewicz, M.A. O'Malley.
Continuous Culture of Anaerobic Fungi Enables Growth and Metabolic Flux Tuning Without Use of Genetic Tools
Bioresource Technology2023
82. K.A. Heom, C. Wangsanuwat, L.V. Butkovich, S.C. Tam, A.R. Rowe, M.A. O’Malley.
Targeted rRNA depletion enables efficient mRNA sequencing in diverse bacterial species and complex co-cultures
mSystems81. S.P. Lillington, M. Hamilton, J.F. Cheng, Y. Yoshikuni, M.A. O'Malley.
Expression and Characterization of Spore Coat CotH Kinases from the Cellulosomes of Anaerobic Fungi (Neocallimastigomycetes)
Protein Expression and Purification80. A. Dementiev, S.P. Lillington, S. Jin, Y. Kim, R. Jedrzejczak, K. Michalska, A. Joachimiak, M.A. O'Malley.
Structure and Enzymatic Characterization of CelD Endoglucanase from the Anaerobic Fungus Piromyces finnis
Applied Microbiology and Biotechnology79. S. Seppälä, T. Gierke, E.E. Schauer, J.L. Brown, M.A. O'Malley.
Identification and Expression of Small Multidrug Resistance Transporters in Early‐Branching Anaerobic Fungi
Protein Science78. J.L. Brown, T. Gierke, L.V. Butkovich, C.L. Swift, V. Singan, C. Daum, K. Barry, I.V. Grigoriev, M.A. O'Malley.
High-Quality RNA Extraction and the Regulation of Genes Encoding Cellulosomes Are Correlated with Growth Stage in Anaerobic Fungi
Frontiers in Fungal Biology77. T.S. Lankiewicz, H. Choudhary, Y. Gao, B. Amer, S.P. Lillington, P.A. Leggieri, J.L. Brown, C.L. Swift, A. Lipzen, H. Na, M. Amirebrahimi, M.K. Theodorou, E.E.K Baidoo, K. Barry, I.V. Grigoriev, V.I. Timokhin, J. Gladden, S. Singh, J.C. Mortimer, J. Ralph, B.A. Simmons, S.W. Singer, M.A. O'Malley.
Lignin Deconstruction by Anaerobic Fungi
Nature Microbiology (Cover article)76. C.T. Han, K.D.Q. Nguyen, M.W. Berkow, S. Hussain, A. Kiani, M. Kinnebrew, M.N. Idso, N. Baxter, E. Chang, E. Aye, E. Winslow, M. Rahman, S. Seppala, M.A. O'Malley, B.F. Chmelka, B. Mertz, S. Han.
Lipid Membrane Mimetics and Oligomerization Tune Functional Properties of Proteorhodopsin
Biophysical Journal2022
75. J.L. Brown, M.A. Perisin, C.L. Swift, M. Benyamin, S. Liu, V. Singan, Y. Zhang, E. Savage, C. Pennacchio, I.V. Grigoriev, M.A. O'Malley.
Co Cultivation of Anaerobic Fungi with Clostridium acetobutylicum Bolsters Butyrate and Butanol Production from Cellulose and Lignocellulose
Journal of Industrial Microbiology and Biotechnology74. U. Neri, Y.I. Wolf, S. Roux, A.P. Camargo, B. Lee, D. Kazlauskas, I.M. Chen, N. Ivanova, L.Z. Allen, D. Paez-Espino, D.A. Bryant, D. Bhaya, RNA Virus Discovery Consortium (including M.A. O'Malley), M. Krupovic, V.V. Dolja, N.C. Kyrpides, E.V. Koonin,
Expansion of the Global RNA Virome Reveals Diverse Clades of Bacteriophages
Cell73. P.A. Leggieri, M.T. Valentine, M.A. O'Malley.
Biofilm Disruption Enhances Growth Rate and Carbohydrate-Active Enzyme Production in Anaerobic Fungi
Bioresource Technology72. M.S. Elshahed, R.A. Hanafy, Y. Cheng, S.S. Dagar, J.E. Edwards, V. Flad, K.O. Fliegerova, G.W. Griffith, S. Kittelmann, M. Lebuhn, M.A. O'Malley, S.M. Podmirseg, K.V. Solomon, J. Vinzelj, D. Young, N.H. Youssef.
Characterization and rank assignment criteria for the Anaerobic Fungi (Neocallimastigomycota)
International Journal of Systematic and Evolutionary Microbiology71. T.S. Lankiewicz, S.P. Lillington, M.A. O’Malley.
Enzyme Discovery in Anaerobic Fungi (Neocallimastigomycetes) Enables Lignocellulosic Biorefinery Innovation
Microbiology and Molecular Biology Reviews70. B.J. Fremin, A.S. Bhatt, N.C. Kyrpides, Global Phage Small Open Reading Frame Consortium (including M.A. O'Malley)
Thousands of Small, Novel Genes Predicted in Global Phage Genomes
Cell Reports69. I.A. Podolsky, E.E. Schauer, S. Seppälä, M.A. O’Malley.
Identification of Novel Membrane Proteins for Improved Lignocellulose Conversion
Current Opinion in Biotechnology68. J.I. Yoo, T.A. Navaratna, P. Kolence, M.A. O’Malley.
GPCR-FEX: A Fluoride-Based Selection System for Rapid GPCR Screening and Engineering
ACS Synthetic Biology2021
67. J.L. Brown, C.L. Swift, S.J. Mondo, S. Seppälä, A. Salamov, V. Singan, B. Henrissat, E. Drula, J.K. Henske, S. Lee, K. LaButti, G. He, M. Yan, K. Barry, I.V. Grigoriev, M.A. O'Malley.
Co‑cultivation of the anaerobic fungus Caecomyces churrovis with Methanobacterium bryantii enhances transcription of carbohydrate binding modules, dockerins, and pyruvate formate lyases on specific substrates
Biotechnology for Biofuels66. E.M. Blair, K.L. Dickson, M.A. O’Malley.
Microbial communities and their enzymes facilitate degradation of recalcitrant polymers in anaerobic digestion
Current Opinion in Microbiology65. P.A. Leggieri, C. Kerdman-Andrade, T.S. Lankiewicz, M.T. Valentine, M.A. O'Malley.
Non-destructive quantification of anaerobic gut fungi and methanogens in co-culture reveals increased fungal growth rate and changes in metabolic flux relative to mono-culture
Microbial Cell Factories64. C.L. Swift, K.B. Louie, B.P. Bowen, C.A. Hooker, K.V. Solomon, V. Singan, C. Daum, C.P. Pennacchio, K. Barry, V. Shutthanandan, J.E. Evans, I.V. Grigoriev, T.R. Northen, M.A. O'Malley.
Co-cultivation of anaerobic fungi with rumen bacteria establishes an antagonistic relationship
MBio63. C.L. Swift, N.G. Malinov, S.J. Mondo, A. Salamov, I.V. Grigoriev, M.A. O'Malley.
A genomic catalog of stress response genes in anaerobic fungi for applications in bioproduction
Frontiers in Fungal Biology62. K.D. Nguyen, M. Vigers, E. Sefah, S. Seppälä, J. Hoover, N.S. Schonenbach, B. Mertz, M.A. O'Malley, S. Han.
Homo-oligomerization of the human adenosine A2A receptor is driven by the intrinsically disordered C-terminus
Biophysical Journal61. I.A. Podolsky, S. Seppälä, H. Xu, Y.S. Jin, M.A. O'Malley.
A SWEET surprise: anaerobic fungal sugar transporters and chimeras enhance sugar uptake in yeast
Metabolic Engineering60. P.A. Leggieri, Y. Liu, M. Hayes, B. Connors, S. Seppälä, M.A. O'Malley, O.S. Venturelli.
Integrating systems and synthetic biology to understand and engineer microbiomes
Annual Review of Biomedical Engineering59. S.P. Lillington, W. Chrisler, C.H. Haitjema, S.P. Gilmore, C.R. Smallwood, V. Shutthanandan, J.E. Evans, M.A. O'Malley.
Cellulosome localization patterns vary across life stages of anaerobic fungi
MBio58. S. Roux, B.G. Paul, S.C. Bagby, S. Nayfach, M.A. Allen, G. Attwood, R. Cavicchioli, L Chistoserdova, R.J. Gruninger, S.J. Hallam, M.E. Hernandez, M. Hess, W. Liu, T.A. McAllister, M.A. O'Malley, X. Peng, V.I. Rich, S.R. Saleska, E.A. Eloe-Fadrosh.
Ecology and molecular targets of hypermutation in the global microbiome
Nature Communications57. C.L. Swift, K.B. Louie, B.P. Bowen, H.M. Olson, S.O. Purvine, A. Salamov, S.J. Mondo, K.V. Solomon, A.T. Wright, T.R. Northen, I.G. Grigoriev, N.P. Keller, M.A. O'Malley.
Anaerobic gut fungi are an untapped reservoir of natural products
Proceedings of the National Academy of Sciences56. L.M.G. Saye, T.A. Navaratna, J.P.J. Chong, M.A. O’Malley, M.K. Theodorou, M. Reilly.
The anaerobic fungi: challenges and opportunities for industrial lignocellulosic biofuel production
Microorganisms55. S.E. Wilken, J.M. Monk, P.A. Leggieri, C.E. Lawson, T.S. Lankiewicz, S. Seppälä, C.G. Daum, J. Jenkins, A.M. Lipzen, S.J. Mondo, K.W. Barry, I.V. Grigoriev, J.K. Henske, M.K. Theodorou, B.O. Palsson, L.R. Petzoid, M.A. O'Malley.
Experimentally validated reconstruction and analysis of a genome-scale metabolic model of an anaerobic Neocallimastigomycota fungus
mSystems54. X. Peng, S.E. Wilken, T.S. Lankiewicz, S.P. Gilmore, J.L. Brown, J.K. Henske, C.L. Swift, A. Salamov, K. Barry, I.V. Grigoriev, M.K. Theodorou, D.L. Valentine, M.A. O'Malley.
Genomic and functional analyses of fungal and bacterial consortia that enable lignocellulose breakdown in goat gut microbiomes
Nature Microbiology (Cover Article)2020
53. S. Nayfach, S. Roux, R. Seshadri, D. Udwary, N. Varghese, F. Schulz, D. Wu, D. Paez-Espino, I. Chen, M. Huntemann, K. Palaniappan, J. Ladau, S. Mukherjee, T.B.K. Reddy, T. Nielsen, E. Kirton, J.P. Faria, J.N. Edirisinghe, C.S. Henry, S.P Jungbluth, D. Chivian, P. Dehal, E.M. Wood-Charlson, A.P. Arkin, IMG/M Data Consortium (including M.A. O'Malley), E.A. Eloe-Fadrosh.
A genomic catalog of Earth’s microbiomes
Nature Biotechnology52. V. Dollhofer, D. Young, S. Seppälä, C. Hooker, N. Youssef, M. Nagler, M. Reilly, Y. Li, K. Fliegerova, Y. Cheng, G.W. Griffith, M. Elshahed, K.V. Solomon, M.A. O'Malley, M.K. Theodorou.
The biotechnological potential of anaerobic gut fungi
Genetics and Biotechnology51. J.I. Yoo, S. Seppälä, M.A. OʼMalley.
Engineered fluoride sensitivity enables biocontainment and selection of genetically modified yeasts
Nature Communications50. C. Wangsanuwat, K. Heom, E. Liu, M.A. O’Malley.
Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion
BMC Genomics49. L.H. Hagen, C.G. Brooke, C.A. Shaw, A.D. Norbeck, H. Piao, M.Ø. Arntzen, H.M. Olson, A. Copeland, N. Isern, A. Shukla, S. Roux, V. Lombard, B. Henrissat, M.A. O'Malley, I.V. Grigoriev, S.G. Tringe, R.I. Mackie, L. Pasa-Tolic, P.B. Pope, M. Hess.
Proteome specialization of anaerobic fungi during ruminal degradation of recalcitrant plant fiber
The ISME Journal48. T.A. Rush, V. Puech-Pagès, A. Bascaules, P. Jargeat, F. Maillet, A. Haouy, A.Q. Maes, C.C. Carriel, D. Khokhani, M. Keller-Pearson, J. Tannous, K.R. Cope, K. Garcia, J. Maeda, C. Johnson, B. Kleven, Q.J. Choudhury, J. Labbe, C. Swift, M.A. O'Malley, J.W. Bok, S. Cottaz, S. Fort, V. Poinsot, J. Ane.
Lipo-chitooligosaccharides as regulatory signals of fungal growth and development
Nature Communications47. S.E. Wilken, P.A. Leggieri, C. Kerdman‐Andrade, M. Reilly, M.K. Theodorou, M.A. O'Malley.
An Arduino-based automatic pressure evaluation system to quantify growth of non‐model anaerobes in culture
AIChE Journal46. S. Seppälä, T.S. Lankiewicz, M. Saxena, J.K. Henske, A.A. Salamov, I.V. Grigoriev, M.A. O'Malley.
Genomic and proteomic biases inform metabolic engineering strategies for anaerobic fungi
Metabolic Engineering Communications45. S.P. Lillington, P.A. Leggieri, K.A. Heom, M.A. O’Malley.
Nature’s recyclers: anaerobic microbial communities drive crude biomass deconstruction
Current Opinion in Biotechnology44. S.P. Gilmore, S.P. Lillington, C.H. Haitjema, R. de Groot, M.A. O'Malley.
Designing chimeric enzymes inspired by fungal cellulosomes
Synthetic and Systems Biotechnology43. J.I. Yoo, P.S. Daugherty, M.A. O’Malley.
Bridging non-overlapping reads illuminates high-order epistasis between distal protein sites in a GPCR
Nature Communications2019
42. S. Seppälä, J.I. Yoo, D. Yur, M.A. O'Malley.
Heterologous transporters from anaerobic fungi bolster fluoride tolerance in Saccharomyces cerevisiae
Metabolic Engineering Communications41. C.L. Swift, J.L. Brown, S. Seppälä, M.A. O’Malley.
Co-cultivation of the anaerobic fungus Anaeromyces robustus with Methanobacterium bryantii enhances transcription of carbohydrate active enzymes
Journal of Industrial Microbiology and Biotechnology40. C.E. Lawson, W.R. Harcombe, R. Hatzenpichler, S.R. Lindemann, F.E. Löffler, M.A. O'Malley, H.G. Martin, B.F. Pfleger, L. Raskin, O.S. Venturelli, D.G. Weissbrodt, D.R. Noguera, K.D. McMahon.
Common principles and best practices for engineering microbiomes
Nature Reviews Microbiology39. S.P. Gilmore, T.S. Lankiewicz, S.E. Wilken, J.L. Brown, J.A. Sexton, J.K. Henske, M.K. Theodorou, D.L. Valentine, M.A. O'Malley.
Top-down enrichment guides in formation of synthetic microbial consortia for biomass degradation
ACS Synthetic Biology38. I.A. Podolsky, S. Seppälä, T.S. Lankiewicz, J.L. Brown, C.L. Swift, M.A. O'Malley.
Harnessing nature's anaerobes for biotechnology and bioprocessing
Annual Review of Chemical and Biomolecular Engineering37. C.L. Swift, I.A. Podolsky, T.S. Lankiewicz, S. Seppälä, M.A. O'Malley.
Linking ‘omics’ to function unlocks the biotech potential of non-model fungi
Current Opinion in Systems Biology2018
36. K.V. Solomon, J.K. Henske, S.P. Gilmore, A. Lipzen, I.V. Grigoriev, D. Thompson, M.A. O'Malley.
Catabolic repression in early-diverging anaerobic fungi is partially mediated by natural antisense transcripts
Fungal Genetics and Biology35. J.K. Henske, S.P. Gilmore, C.H. Haitjema, K.V. Solomon, M.A. O'Malley.
Biomass‐degrading enzymes are catabolite repressed in anaerobic gut fungi
AIChE Journal34. X. Peng, C.L. Swift, M.K. Theodorou, M.A. O’Malley.
Methods for genomic characterization & maintenance of anaerobic fungi
Methods in Molecular Biology: Fungal Genomics, Springer Protocols Series33. J.I. Yoo, M.A. O’Malley.
Tuning vector stability and integration frequency elevates functional GPCR production and homogeneity in Saccharomyces cerevisiae
ACS Synthetic Biology32. K.V. Solomon, C.H. Haitjema, J.K. Henske, S.P. Gilmore, D. Borges-Rivera, A. Lipzen, H.M. Brewer, S.O. Purvine, A.T. Wright, M.K. Theodorou, I.V. Grigoriev, A. Regev, D.A. Thompson, M.A. O'Malley.
Early-branching gut fungi possess a large, comprehensive array of biomass-degrading enzymes
Science31. J.K. Henske, S.D. Springer, M.A. O'Malley, A. Butler.
Substrate-based differential expression analysis reveals control of biomass degrading enzymes in Pycnoporus cinnabarinus
Biochemical Engineering Journal30. S.E. Wilken, M. Saxena, L.R. Petzold, M.A. O’Malley.
In silico identification of microbial partners to form consortia with anaerobic fungi
Processes2017
29. J.K. Henske, S.P. Gilmore, D. Knop, F.J. Cunningham, J.A. Sexton, C.R. Smallwood, V. Shutthanandan, J.E. Evans, M.K. Theodorou, M.A. O'Malley.
Transcriptomic characterization of Caecomyces churrovis: a novel, non-rhizoid forming lignocellulolytic anaerobic fungus
Biotechnology for Biofuels28. J.K. Henske, S.E. Wilken, K.V. Solomon, C.R. Smallwood, V. Shutthanandan, J.E. Evans, M.K. Theodorou, M.A. O'Malley.
Metabolic characterization of anaerobic fungi provides a path forward for bioprocessing of crude lignocellulose
Biotechnology and Bioengineering27. S. Seppälä, D. Knop, K.V. Solomon, M.A. O’Malley.
The importance of sourcing enzymes from non-conventional fungi for metabolic engineering and biomass breakdown
Metabolic Engineering26. J.E. Edwards, R.J. Forster, T.M. Callaghan, V. Dollhofer, S.S. Dagar, Y. Cheng, J. Change, S. Kittelmann, K. Fliegerova, A.K. Puniya, J.K. Henske, S.P. Gilmore, M.A. O'Malley, G.W. Griffith, H. Smidt.
PCR and omics-based techniques to study the diversity, ecology, and biology of anaerobic fungi: insights, challenges, and opportunities
Frontiers in Microbiology25. S.P. Gilmore, J.K. Henske, J.A. Sexton, K.V. Solomon, S. Seppälä, J.I. Yoo, L.M. Huyett, A. Pressman, J.Z. Cogan, V. Kivenson, X. Peng, Y. Tan, D.L. Valentine, M.A. O'Malley.
Genomic analysis of methanogenic archaea reveals a shift towards energy conservation
BMC Genomics24. C.H. Haitjema, S.P. Gilmore, J.K. Henske, K.V. Solomon, R. De Groot, A. Kuo, S.J. Mondo, A.A. Salamov, K. LaButti, Z. Zhao, J. Chiniquy, K. Barry, H.M. Brewer, S.O. Purvine, A.T. Wright, M. Hainaut, B. Boxma, T. van Alen, J.H.P. Hackstein, B. Henrissat, S.E. Baker, I.V. Grigoriev, M.A. O'Malley.
A parts list for fungal cellulosomes revealed by comparative genomics
Nature Microbiology23. S.J. Mondo, R.O. Dannebaum, R.C. Kuo, K.B. Louie, A.J. Bewick, K. LaButti, S. Haridas, A. Kuo, A. Salamov, S.R. Ahrendt, R. Lau, B.P. Bowen, A. Lipzen, W. Sullivan, B.B. Andreopoulos, A. Clum, E. Lindquist, C. Daum, T.R. Northen, G. Kunde-Ramamoorthy, R.J. Schmitz, A. Gryganskyi, D. Culley, J. Magnuson, T.Y. James, M.A. O'Malley, J.E. Stajich, J.W. Spatafora, A. Visel, I.V. Grigoriev
Widespread adenine N6-methylation of active genes in fungi
Nature Genetics22. J. Niu, D.J. Lunn, A. Pusuluri, J.I. Yoo, M.A. O'Malley, S. Mitragotri, H.T. Soh, C.J. Hawker.
Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization
Nature Chemistry2016
21. S. Seppälä, K.V. Solomon, S.P. Gilmore, J.K. Henske, M.A. O'Malley.
Mapping the membrane proteome of anaerobic gut fungi identifies a wealth of carbohydrate binding proteins and transporters
Microbial Cell Factories20. X.Peng, S.P. Gilmore, M.A. O’Malley.
Microbial communities for bioprocessing: lessons learned from nature
Current Opinion in Chemical Engineering19. N.S. Sconenbach, M.D. Rieth, S. Han, M.A. O’Malley.
Adenosine A2a receptors form distinct oligomers in protein detergent complexes
FEBS Letters18. J.L. Guerrero, P.S. Daugherty, M.A. O'Malley.
Emerging technologies for protease engineering: New tools to clear out disease
Biotechnology and Bioengineering17. K. V. Solomon, J. K. Henske, C. H. Haitjema, S. P. Gilmore, M. K. Theodorou, M.A. O’Malley.
Fungal diversity notes 253-366: taxonomic and phylogenetic contributions to fungal taxa
Fungal Diversity16. K.V. Solomon, J.K. Henske, M.K. Theodorou, M.A. O'Malley.
Robust and effective methodologies for cryopreservation and DNA extraction from anaerobic gut fungi
Anaerobe15. K.V. Solomon, E. Ovadia, F. Yu, W. Mizunashi, M.A. O'Malley.
Mitochondrial targeting increases specific activity of a heterologous valine assimilation pathway in Saccharomyces cerevisiae
Metabolic Engineering Communications14. J.L. Guerrero, M.A. O'Malley, P.S. Daugherty.
Intracellular FRET-based screen for redesigning the specificity of secreted proteases
ACS Chemical Biology2015
13. S.P. Gilmore, J.K. Henske, M.A. O'Malley.
Driving biomass breakdown through engineered cellulosomes
Bioengineered2014
12. M.A. O'Malley, N. Schonenbach, S. Hussain.
Structure and function of G protein-coupled receptor oligomers: implications for drug
WIRES Nanomedicine11. K.V. Solomon, C.H. Haitjema, D.A. Thompson, M.A. O'Malley.
Extracting data from the muck: deriving biological insight from complex microbial communities and non-model organisms with next generation sequencing
Current Opinion in Biotechnology10. C.H. Haitjema, K.V. Solomon, J.K. Henske, M.K. Theodorou, M.A. O'Malley.
Anaerobic gut fungi: advances in isolation, culture, and cellulolytic enzyme discovery for biofuel production
Biotechnology and Bioengineering2011
9. M.A. O'Malley, M.K. Theodorou, C.A. Kaiser.
Evaluating expression and catalytic activity of anaerobic fungal fibrolytic enzymes native to Piromyces sp. E2 in Saccharomyces cerevisiae
Environmental Progress & Sustainable Energy8. M.A. O'Malley.
Neuromethods, Vol. 60: Methods for the Discovery and Characterization of G Protein‐Coupled Receptors
ChemBioChem7. M.A. O'Malley, M.E. Helgeson, N.J. Wagner, A.S. Robinson.
Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor
Biophysical Journal6. M.A. O'Malley, M.E. Helgeson, N.J. Wagner, A.S. Robinson.
The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity
Biophysical Journal2010
5. M.A. O'Malley, A.N. Naranjo, T. Lazarova, A.S. Robinson.
Analysis of Adenosine A2a Receptor Stability: Effects of Ligands and Disulfide Bonds
Biochemistry2009
4. M.A. O'Malley, J.D. Mancini, C.L. Young, E.C. McCusker, D. Raden, A.S. Robinson.
Progress toward heterologous expression of active G‐protein‐coupled receptors in Saccharomyces cerevisiae: Linking cellular stress response with translocation
Protein Science2008
3. E.C. McCusker, S.E. Bane, M.A. O'Malley, A.S. Robinson.
Heterologous GPCR expression: a bottleneck to obtaining crystal structures
Biotechnology Progress2. A. Wedekind, M.A. O'Malley, R.T. Niebauer, A.S. Robinson.
Optimization of the Human Adenosine A2a Receptor Yields in Saccharomyces cerevisiae
Biotechnology Progress2007
1. M.A. O'Malley, T. Lazarova, Z.T. Britton, A.S. Robinson.
High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor
Journal of Structural BiologyPatents
- M.A. O'Malley, I.A. Podolsky, S. Seppala.
US Patent 12,098,171: Hybrid sugar transporters with altered sugar transport activity and uses thereof. - M.A. O'Malley, K. Solomon, C. Haitjema.
US Patent 12,037,371: Proteins from anaerobic fungi and uses thereof. - M.A. O'Malley, K. Solomon, C. Haitjema.
US Patent 11,021,524: Proteins from anaerobic fungi and uses thereof. - MA. O'Malley, K. Solomon, C. Haitjema.
US Patent 10,717,768: Proteins from anaerobic fungi and uses thereof. - M.A. O'Malley, K. Solomon, W. Mizunashi, F. Yu.M
US Patent 10,676,766: Biological production of methyl methacrylate.